The Chinese Livestock and Poultry Breeding ›› 2023, Vol. 19 ›› Issue (6): 24-28.

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Application of Liquid Chip Technology in Animal Genetics and Breeding

Zhang Geyang1,2, Lv Shijie1, Zhu Xiaoting1, Zhai Yaying1,2, Zhang Zhihao1,2, Shi Qiaoting1, Zhang Zijing1, Qu Junfeng3, Chen Fuying1, Wang Eryao1,*   

  1. 1. Institute of Animal Science of Henan Academy of Agricultural Sciences/Henan Key Laboratory of Farm Animal Breeding and Nutritional Regulation, Zhengzhou, 450002, Henan;
    2. Animal Science and Technology College of Henan Agricultural University, Zhengzhou, 450002, Henan;
    3. Henan Science and Technology Innovation Promotion Center, Zhengzhou, 450008, Henan
  • Received:2023-05-18 Online:2023-06-26 Published:2023-07-26

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Abstract: Liquid chip technology is an advanced high-throughput molecular detection technology in recent years, integrating various technical advantages such as flow cytometry, fluorescent microspheres, laser technology, digital signal processing technology, etc., with the advantages of speed, simplicity, sensitivity, accuracy, and low cost. Compared with other detection technologies, liquid chip technology can detect multiple biomolecular indicators at the same time, such as proteins, nucleic acids, metabolites, etc. In animal genetic breeding, these molecular parameters can be used in important fields such as disease gene mapping, population fertility evaluation, kinship research, and genetic diversity analysis. This paper introduces the principle, advantages, and disadvantages of liquid phase chips and their application in animal genetic breeding, and provides a reference for assisting the development of new technologies for animal genetic breeding detection.

Key words: Liquid chip technology, Genetic breeding, Application

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